2024 Proheart dosing

What is ProHeart 12? ProHeart 12 is a medication that prevents heartworm disease in dogs 12 months of age and older. Your veterinarian gives it to your dog via an injection and it protects your dog from developing heartworm disease for 12 full months. ProHeart 12 . also treats common hookworm infections your dog may have at the time of injection.. Cassata cake columbus ohio

The solution has come in the form of heartworm prevention shots that protect your dog for six months or a full year—ProHeart 6 and ProHeart 12. While the ProHeart 6 (six-month) heartworm prevention injection has been approved and available since 2008, the ProHeart 12 (yearly) injection was only recently approved by the US Food & Drug Administration …The lethal dose of diphenhydramine, the generic name of Benadryl, varies significantly from person to person because of differences in weight and metabolism.ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by . Dirofilaria immitis. for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum. and . Uncinaria stenocephala) infections. DOSAGE AND ADMINISTRATIONClient Information Sheet. Review this information with your veterinarian each time your dog receives ProHeart 6. When your veterinarian prescribes medicine for your dog, it’s sometimes hard to remember all the information discussed during the visit. This sheet is provided as a summary, but if. you have any additional questions you should ...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,Proheart 12 · Revolution Plus · Rimadyl ... Home / Products / Beef / Overview / Dosing & Administration ... Dosing & Administration. It doesn't take much&...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofBackground The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× (control); 1× ...with ProHeart 6 either 1, 3, or 5 times at the recommended dose of 0.17 mg/kg did not demonstrate any clinical signs, laboratory findings, or necropsy lesions associated with systemic or target organ toxicity.2In addition, when ProHeart 6 was administered toProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary productsIn a well-controlled 605-day US field study, two doses of ProHeart 12 were administered subcutaneously at a dosage of 0.5 mg/kg (0.23 mg/lb), 12 months apart. A total of 235, 226 and 222 ProHeart 12-treated dogs completed the heartworm testing (adult heartworm antigen and microfilariae) on Days 365, 480 and 605, respectively.ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofLearn how to get certified for ProHeart, a convenient and effective heartworm prevention for dogs, by watching a video from Zoetis.Certification is required prior to the purchase and administration of ProHeart® 6 (moxidectin) and ProHeart® 12 (moxidectin) in your clinic. Certification involves a one-time commitment to watch a video providing product education. Veterinary technicians are encouraged to certify so that they can also administer ProHeart 6 and ProHeart 12. dose based on the dog’s weight at the time of treatment. Do not overdose growing puppies in anticipation of their expected adult weight. The following dosage chart may be used as a guide. Some dogs treated with ProHeart 6 in laboratory effectiveness studies developed transient, localized inflammatory injection DOSAGE CHART site reactions. This extended-release injectable contains moxidectin as its active ingredient, a robust parasiticide targeting heartworm larvae. This grants 12 months of solid protection against canine heartworms with just one dose of ProHeart 12, giving dog owners a reassuring sense of security that their pet is protected year-round. An injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that were inoculated with infective larvae 365 days after receiving a dose of 0.5 mg/kg. 2,3 INDICATIONS. IMMITICIDE ® (melarsomine dihydrochloride) Sterile Powder is indicated for the treatment of stabilized Class 1, 2, and 3 heartworm disease caused by immature to mature adult infections of Dirofilaria immitis in dogs. CONTRAINDICATIONS: IMMITICIDE is contraindicated in dogs with very severe (Class 4) heartworm disease.Dosing considerations. Before initiating JARDIANCE, assess volume status and renal function in patients with impaired renal function (eGFR <60 mL/min/1.73 m2), elderly patients, or patients on loop diuretics. In patients with volume depletion, correct this condition before initiating JARDIANCE. After initiating, monitor for signs and symptoms ...Find out how to get certified for ProHeart , a convenient and effective way to prevent heartworm disease in dogs. Zoetis, the leading animal health company.In people that are not tolerant of opioids, a single dose of 40 milligrams or a total daily dose of 80 milligrams of oxycodone has the potential to cause fatal respiratory depressi...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,Heartgard: The Monthly Protector. Heartgard is a monthly oral medication that prevents heartworm disease, as well as treats and controls roundworms and hookworms. Key Benefits: Monthly dosing: Allows for flexibility and ease of discontinuation if necessary. Palatable chew: Dogs often see it as a treat, making administration easy.Heartworm disease. Heartworms are parasites that are able to live inside the arteries of the lung and chambers of a pet’s heart and feed on surrounding blood. In severe cases heartworms can grow up to 30cm long and 2cm thick in populations of over 200. The offspring of a heartworm are more commonly referred to as Microfilariae, which can be ...ProHeart 12 Prescribing Information. ProHeart® 6 (moxidectin) delivers 6 months of heartworm disease prevention for dogs with 1 shot. Learn more here.heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent andProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofAre you guilty of missing your pets monthly heartworm prevention? With our busy lifestyles, this can be easy to do. The only problem is, heartworm is the one parasite that can cause death in our pets...In today’s digital age, the way we consume information and entertainment has drastically changed. Gone are the days of flipping through physical books or magazines to get our daily...ProHeart 12 is a veterinary injectable suspension for dogs to prevent and treat heartworm and hookworm infections. Learn about the dosage, administration, indications, contraindications, and risk minimization action plan of ProHeart 12.Jul 9, 2018 ... ... proheart early or late up to 2 weeks after ... what I would do if your dog misses a dose, dose ... dosing day and dose again in 30 days or whatever ...The constituted suspension is for subcutaneous injection at the rate of 0.05 mL/kg body weight to provide 0.17 mg moxidectin/kg. ProHeart 6 can be administered to dogs 6 months of age and older. For growing dogs, dose to the average weight during the 6 month effective period. Administration may be repeated at 6 months intervals.Our Purpose. At Zoetis we understand that dogs aren’t just pets, they are members of the family. We encourage every dog owner to visit a veterinarian on a regular basis. Annual check-ups and preventive care are the best ways to make sure your dog (s) stay active and healthy. Antibiotics, parasite control, skin issues, pain management and ...ProHeart® 12 is an injectable heartworm disease preventative that provides 12 months of continuous protection against heartworm disease with a single veterinary-administered dose. See products. 10 ml, 1/Pkg (With 1 Client Information Pad)ProHeart 6 administered at 3 times the recommended dose in dogs with patent heartworm infections and up to 5 times the recommended dose in ivermectin-sensitive collies did not cause any adverse reactions. ProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs.The solution has come in the form of heartworm prevention shots that protect your dog for six months or a full year—ProHeart 6 and ProHeart 12. While the ProHeart 6 (six-month) heartworm prevention injection has been approved and available since 2008, the ProHeart 12 (yearly) injection was only recently approved by the US Food & Drug Administration …One disadvantage to the "split-dose" method, in addition to the expense, is the need for 2 months' exercise restriction. In 55 dogs with severe heartworm disease (HWD) and treated in this 3-dose manner, 96% had a good or very good outcome with >98% negative for antigenemia 90 days post-therapy. 19 Although symptomatic and even fatal PTE can ...This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or …ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for 6 months; however, against a ML-resistant strain, ProHeart 6 was ineffective at the end of 6 months . ProHeart 6 is a medication that prevents heartworm disease in dogs 6 months of age and older. ProHeart 6 is given by injection by your veterinarian. One injection of ProHeart 6 protects your dog from heartworm disease for 6 complete months. ProHeart 6 also treats common hookworm infections that may be present at the time of injection. Effective Protection: ProHeart 6 provides continuous protection against heartworm larvae, ensuring that dogs are safeguarded against the potentially devastating consequences of heartworm disease. Cost-Effectiveness: While the initial cost of ProHeart 6 may be higher than monthly preventatives, its twice-yearly dosing schedule can be more cost ... ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent efectiveness has not been established for this indication. Re-infection with A. caninum and U. stenocephala may occur Find out how to get certified for ProHeart , a convenient and effective way to prevent heartworm disease in dogs. Zoetis, the leading animal health company. Both ProHeart 6 and ProHeart 12 are hailed for their efficacy and safety, with the primary difference lying in the duration of protection and the age at which they can be administered. While ProHeart 6 offers a great starting point for younger dogs, ProHeart 12 steps in as a convenient, longer-lasting alternative for dogs over 1 year of age.Dosing considerations. Before initiating JARDIANCE, assess volume status and renal function in patients with impaired renal function (eGFR <60 mL/min/1.73 m2), elderly patients, or patients on loop diuretics. In patients with volume depletion, correct this condition before initiating JARDIANCE. After initiating, monitor for signs and symptoms ...ProHeart 12 has been proven effective in preventing heartworm disease for 12 months. Simparica protects all month long without losing effectiveness toward the end of the month like some other products.6-11 Just 1 dose of ProHeart 12 prevents heartworm‡ 12Aug 28, 2014 ... A: A bi-annual injectable heartworm preventive containing moxidectin (ProHeart. ®. 6,. Zoetis) that is labeled for the prevention of heartworm ... ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months, Background The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods Study 1: safety …ProHeart 12 is a veterinary injectable suspension for dogs to prevent and treat heartworm and hookworm infections. Learn about the dosage, administration, indications, contraindications, and risk minimization action plan of ProHeart 12.ProHeart Injection is a veterinarian-administered injectable solution that provides long-term protection against heartworm disease in dogs. Depending on the version (ProHeart 6 or ProHeart 12), it can offer 6 or 12 months of …Dose promptly after drawing into dosing syringe. If administration is delayed, gently roll the dosing sy ringe prior to injection to maintain a uniform suspension and accurate dosing. Using aseptic technique, inject the product subcutaneously in the left or right side of the dorsum of the neck cranial to the s capula.DESCRIPTION. ProHeart 12 (moxidectin) for extended-release injectable suspension consists of two separate vials: one vial contains 10% moxidectin sterile microspheres; and the second vial contains a specifically formulated sterile vehicle for constitution with the microspheres. A clear or translucent appearance of the vehicle is normal.ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,INDICATIONS. IMMITICIDE ® (melarsomine dihydrochloride) Sterile Powder is indicated for the treatment of stabilized Class 1, 2, and 3 heartworm disease caused by immature to mature adult infections of Dirofilaria immitis in dogs. CONTRAINDICATIONS: IMMITICIDE is contraindicated in dogs with very severe (Class 4) heartworm disease.Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewable—for protection against: *Amblyomma americanum, Amblyomma maculatum, Dermacentor variabilis, Ixodes scapularis, Rhipicephalus sanguineus. †Toxocara canis, Toxascaris leonina, Ancylostoma caninum and Uncinaria ... ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent efectiveness has not been established for this indication. Re-infection with A. caninum and U. stenocephala may occur The ProHeart debate. In January, the Food and Drug Administration's Veterinary Medicine Advisory Committee and consultants heard presentations by the FDA Center for Veterinary Medicine and Fort Dodge Animal Health on the safety of ProHeart 6 (sustained release injectable moxidectin). This past September, Fort Dodge voluntarily …ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for …Jul 2, 2019 · The effectiveness of ProHeart® 12 for the treatment of existing larval and adult hookworms was established by referencing the data presented in the Freedom of Information Summaries for the original approval of ProHeart® 6 (moxidectin) dated June 6, 2001 (NADA 141-189), and the supplemental approval dated June 13, 2002. 0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation.Trazodone can be lethal if more then the prescribed dose is taken, but instances are rare, according to MedlinePlus. The average dose for an outpatient adult ranges from 150 millig...In today’s fast-paced world, staying informed about the latest news is more important than ever. With the advancement of technology, we now have access to news at our fingertips th...ProHeart 6 is a veterinary drug for dogs to prevent and treat heartworm and hookworm infections. It is a two-part sustained release product with 3.4 mg moxidectin per vial. The recommended dose is 0.05 mL per kg body weight, subcutaneously, every six months. The web page provides dosage chart, injection technique, risk minimization action plan, and contraindications.Jun 9, 2020 ... If you insist on making the comparison, the fluralaner (B) dose is 10x the afoxolaner (NS) dose, or ~3x if you consider 3 monthly doses vs 1 ...0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation.Proheart: an injectable heartworm preventative, containing moxidectin. ... This product is used in dogs who seem sensitive to oral medications. Dosing on all ... One disadvantage to the "split-dose" method, in addition to the expense, is the need for 2 months' exercise restriction. In 55 dogs with severe heartworm disease (HWD) and treated in this 3-dose manner, 96% had a good or very good outcome with >98% negative for antigenemia 90 days post-therapy. 19 Although symptomatic and even fatal PTE can ... ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by . Dirofilaria immitis. for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum. and . Uncinaria stenocephala) infections. DOSAGE AND ADMINISTRATION Heartworm disease. Heartworms are parasites that are able to live inside the arteries of the lung and chambers of a pet’s heart and feed on surrounding blood. In severe cases heartworms can grow up to 30cm long and 2cm thick in populations of over 200. The offspring of a heartworm are more commonly referred to as Microfilariae, which can be ...heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent effectiveness has not been established for this indication. Re-infection with A. caninum andPurpose: To determine the effects on dogs of prolonged administration of moxidectin tablets at ten times the recommended an elevated dose. Animals: Two collies (1 male, 1 female), eight weeks of age. Dosage form: tablets. Dose Levels and Regimen: moxidectin was administered at 30 mcg /kg body weight for twelve days.ProHeart Injection is a veterinarian-administered injectable solution that provides long-term protection against heartworm disease in dogs. Depending on the version (ProHeart 6 or ProHeart 12), it can offer 6 or 12 months of …ProHeart 12 is indicated for use in dogs 12 months of age and older for the accurate dosing calculate each dose based on the dog's weight at the time ... proheart pi ProHeart® 6(moxidectin) ProHeart 6 is indicated for use in dogs six months of age and older for the calculate each dose based on the dog's weight at the time of treatment. proheartcis piProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,A single dose of ProHeart® 12 was 100% effective in preventing heartworm disease in dogs for a full year in both laboratory and field studies. The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in dogs for 12 months was …PROHEART a monthly heartworm preventative tablet. HEARTGUARD a monthly heartworm prevention medication which is available as a 'chewable' treat or as a plain ...Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Absence of Humoral Response After Two-Dose SARS-CoV-2 Messenger RNA Vacci...ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary productsEvidence of Efficacy for Moxidectin Heartworm Disease Prevention An injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that were inoculated with infective larvae 365 days after receiving a dose of 0.5 mg/kg. 2,3Popular At The Moment. Zoetis Learning Solutions. Building Healthy Herds. Residue Free Guarantee.The first dose of ProHeart should be given to dogs in accordance with the label. ProHeart 6 is indicated for healthy dogs at least 6 months of age or older. ProHeart 12 is indicated for healthy dogs at least 12 months of age or older.DESCRIPTION. ProHeart 12 (moxidectin) for extended-release injectable suspension consists of two separate vials: one vial contains 10% moxidectin sterile microspheres; and the second vial contains a specifically formulated sterile vehicle for constitution with the microspheres. A clear or translucent appearance of the vehicle is normal.Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in Revolution Plus, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders.ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. ProHeart 6 (moxidectin) Dosage And AdministrationProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,It’s available in four dosing sizes (2-8 lbs., 8.1-25 lbs., 25.1-50 lbs., and 50.1-100 lbs.). Dogs over 100 pounds can still take this medication but will require a combination of chewables for appropriate dosing. Dogs must be at least 2 pounds in size and 6 weeks or older to take this prevention. Simparica TrioCertification is required prior to the purchase and administration of ProHeart® 6 (moxidectin) and ProHeart® 12 (moxidectin) in your clinic. Certification involves a one-time commitment to watch a video providing product education. Veterinary technicians are encouraged to certify so that they can also administer ProHeart 6 and ProHeart 12.

ProHeart 6 is an injectable heartworm preventive medication that can be used in healthy dogs 6 months of age or older. ProHeart 6 is not for use in cats. ProHeart 6 injections are given once every 6 months by your veterinarian. Your veterinarian may recommend a complete physical examination and obtain a thorough health history before .... Wake forest sdn 2023 2024

Are you looking for a way to deepen your faith and connect with God? Daily devotionals are an excellent way to do just that. Devotionals provide a daily dose of spiritual guidance,...A single dose of ProHeart® 12 was 100% effective in preventing heartworm disease in dogs for a full year in both laboratory and field studies. The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in dogs for 12 months was …at the recommended dose rate of 0.17 mg moxidectin/kg body weight is the tissue larval stage. The larval and adult stages of the canine hookworms, Ancylostoma caninum and Uncinaria stenocephala, are susceptible. Following injection with ProHeart 6, peakAre you guilty of missing your pets monthly heartworm prevention? With our busy lifestyles, this can be easy to do. The only problem is, heartworm is the one parasite that can cause death in our pets...Conclusion: A single subcutaneous injection of ProHeart® 12, at a dose of 0.5 mg moxidectin/kg body weight, was 100% effective in preventing the development of D. immitis infections in dogs inoculated with third-stage larvae (L3) 365 days after treatment. 2. Dose Confirmation Study.This extended-release injectable contains moxidectin as its active ingredient, a robust parasiticide targeting heartworm larvae. This grants 12 months of solid protection against canine heartworms with just one dose of ProHeart 12, giving dog owners a reassuring sense of security that their pet is protected year-round.A single dose of 7.5 mg/kg (3X the recommended dose) can result in pulmonary inflammation, edema, and death. Daily administration of these doses for 14 days caused renal damage in healthy dogs. Adverse reactions, primarily at the injection sites, were seenThe animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.Smoothies are a great way to get your daily dose of fruits and vegetables, while also enjoying a delicious and refreshing drink. Whether you’re looking for a healthy breakfast or a...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofA single dose of ProHeart® 12 was 100% effective in preventing heartworm disease in dogs for a full year in both laboratory and field studies. The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in dogs for 12 months was ....

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